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Lamictal, the Glaxo Smith Kline drug is used to treat epilepsy and bipolar disorder, has been linked to certain birth defects including cleft palate or lip exposed to the drug during pregnancy. According to a Wall St. Journal article ” After discussions with Health Canada in August, Glaxo said the cleft-palate deformity was detected at “an elevated rate” in infants whose mothers took the drug during the first three months of pregnancy, compared with others who weren’t exposed to the drug.”

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