The FDA is reviewing diet drugs Alli and Xenical after 32 adverse event reports associated the drugs with liver injury. Alli is manufactured and marketed by GlaxoSmithKline and is available as an over-the-counter weight loss supplement. Xenical, which contains twice the dose of orlistat, is a prescription drug that’s manufactured by Roche and marketed by GlaxoSmithKline.
All of the reported liver injuries occured outside of the United States and 27 of the patients were hospitalized with six reports of liver failure. All but two of the adverse event reports concerned the stronger prescription drug Xenical.
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